Diabetes Control and Cardiovascular Risk, Part II: Intensive Glucose Control - UKPDS Follow-Up
نویسندگان
چکیده
منابع مشابه
10-year follow-up of intensive glucose control in type 2 diabetes.
BACKGROUND During the United Kingdom Prospective Diabetes Study (UKPDS), patients with type 2 diabetes mellitus who received intensive glucose therapy had a lower risk of microvascular complications than did those receiving conventional dietary therapy. We conducted post-trial monitoring to determine whether this improved glucose control persisted and whether such therapy had a long-term effect...
متن کاملEffect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group.
BACKGROUND In patients with type 2 diabetes, intensive blood-glucose control with insulin or sulphonylurea therapy decreases progression of microvascular disease and may also reduce the risk of heart attacks. This study investigated whether intensive glucose control with metformin has any specific advantage or disadvantage. METHODS Of 4075 patients recruited to UKPDS in 15 centres, 1704 overw...
متن کاملImplementing intensive control of blood glucose concentration and blood pressure in type 2 diabetes in England: cost analysis (UKPDS 63).
OBJECTIVE To estimate the incremental cost of implementing policies for intensive control of blood glucose concentration and blood pressure for all patients with type 2 diabetes in England. DESIGN Extrapolation of resource use and cost data derived from a randomised controlled trial. SETTING General practice, outpatient care, and inpatient care. POPULATION Trial population with diagnosed ...
متن کاملFollow-up of blood-pressure lowering and glucose control in type 2 diabetes.
BACKGROUND In the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) factorial trial, the combination of perindopril and indapamide reduced mortality among patients with type 2 diabetes, but intensive glucose control, targeting a glycated hemoglobin level of less than 6.5%, did not. We now report results of the 6-year post-trial foll...
متن کاملIntensive glucose control versus conventional glucose control for type 1 diabetes mellitus.
BACKGROUND Clinical guidelines differ regarding their recommended blood glucose targets for patients with type 1 diabetes and recent studies on patients with type 2 diabetes suggest that aiming at very low targets can increase the risk of mortality. OBJECTIVES To assess the effects of intensive versus conventional glycaemic targets in patients with type 1 diabetes in terms of long-term compli...
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ژورنال
عنوان ژورنال: Preventive Cardiology
سال: 2009
ISSN: 1520-037X,1751-7141
DOI: 10.1111/j.1751-7141.2008.00020.x